Founded in 1981, Molnár-Institute focuses on strategies for improving the efficiency and success of modern HPLC. Our state-of-the-art HPLC modelling software, DryLab supports chromatographers worldwide in method development, optimisation, troubleshooting, robustness testing, and training.
HPLC Method Development
Using real data from a minimal number of experimental runs, DryLab builds selectivity maps depicting the interaction of the most important parameters influencing an HPLC separation. Our systematic, guided method development process reduces development time from weeks to hours, and helps users optimise a wide range of parameters based on their specific method requirements. Simultaneously, it also minimises expensive trail-and-error approaches to method refinement.more
Quality by design (QbD) Approach for Analytical Methods
DryLab enables easy compliance with regulatory (QbD) standards through its systematic approach to HPLC method development, in which the interaction of all influential method parameters is assessed. Our cube feature provides an intuitive visualisation of the design space and allows for increased regulatory flexibility, as movements with the design space are not considered a change in the method.
Robustness Hesting for Method Validation
Robustness testing, an important part of the validation process, determines if a method can be used routinely without producing out of specification (OoS) results. DryLab's robustness testing features help users achieve a 100% success rate in routine applications by statistical testing of the method's robustness thresholds.
DryLab User Training Courses
These courses teach basic principles and technologies for the development of robust and transferable HPLC methods, with the help of the leading method development software suite DryLab®.
Topics covered include the development of new methods, adjustment of old ones, improvement of problematic methods, and the reduction of run time while preserving the desired selectivity. Molnár-Institute also offers a course of Quality by Design (QbD) for HPLC, using DryLab® to support this modern approach to HPLC method development. You can find more information by contacting Molnár-Institute using the form below.less
DryLab 3D Demo
The Animation shows a scan through the 3D Robustness Space
DryLab Cube Presentation
Applied Chromatography from the Molnár-Institute
DryLab HPLC Method Development Software 3D Cube
The Animation shows a scan through the 3D Robustness Space, this illus...
Molnár Institute at Pittcon 2012
Molnár-Institute for Applied Chromatography
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Computer assisted liquid chromatographic method development for the separation of therapeutic proteins
This review summarizes the use of computer assisted liquid chromatographic method development for the analytic...
Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatography, part 1: optimization of the mobile phase
The goal of this work is to provide some recommendations for method development in HIC using mon- oclonal anti...
Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part I: Salt gradient approach
Ion exchange chromatography (IEX) is a historical technique widely used for the detailed characterization of t...
Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part II: pH gradient approach
This work shows that retention and resolution can be modelled in cation exchange pH gradient mode, based on on...
Molnár-Institute for Applied Chromatography
- Malvern Panalytical Malvern Panalytical is a leading provider of scientific instrumen...
- NSF International, Pharma Biotech Providing pharmaceutical consulting, pharmaceutical auditing, pha...
- Dr Deborah Huck-Jones Product Manager for Analytical Imaging Dr Deborah Huck-Jones is Product Manager for Analytical Imaging a...
- Martin Lush, MSc, FIBMS, PG Dip, EU Qualified Person Global Vice President, Pharma Biotech an... Martin Lush has over 30 years’ experience in the pharmaceutical a...
- Managing Critical GMP Incidents and How to Reduce the Consequences and Risk of Recurrence Presented by: Rachel Carmichael - Executive Director, Pharma...
- Shaping the Role of the QP: Now and for the Future <strong>Webinar Presented by: Mike Halliday - Executive Vice...