Molnár-Institute for Applied Chromatography

DryLab Software for UHPLC Method Development

Founded in 1981, Molnár-Institute focuses on strategies for improving the efficiency and success of modern HPLC. Our state-of-the-art HPLC modelling software, DryLab supports chromatographers worldwide in method development, optimisation, troubleshooting, robustness testing, and training.

HPLC Method Development

Using real data from a minimal number of experimental runs, DryLab builds selectivity maps depicting the interaction of the most important parameters influencing an HPLC separation. Our systematic, guided method development process reduces development time from weeks to hours, and helps users optimise a wide range of parameters based on their specific method requirements. Simultaneously, it also minimises expensive trail-and-error approaches to method refinement.

Quality by design (QbD) Approach for Analytical Methods

DryLab enables easy compliance with regulatory (QbD) standards through its systematic approach to HPLC method development, in which the interaction of all influential method parameters is assessed. Our cube feature provides an intuitive visualisation of the design space and allows for increased regulatory flexibility, as movements with the design space are not considered a change in the method.

Robustness Hesting for Method Validation

Robustness testing, an important part of the validation process, determines if a method can be used routinely without producing out of specification (OoS) results. DryLab's robustness testing features help users achieve a 100% success rate in routine applications by statistical testing of the method's robustness thresholds.

DryLab User Training Courses

These courses teach basic principles and technologies for the development of robust and transferable HPLC methods, with the help of the leading method development software suite DryLab®.

Topics covered include the development of new methods, adjustment of old ones, improvement of problematic methods, and the reduction of run time while preserving the desired selectivity. Molnár-Institute also offers a course of Quality by Design (QbD) for HPLC, using DryLab® to support this modern approach to HPLC method development. You can find more information by contacting Molnár-Institute using the form below.

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Contact details

Phone

+49 30 421 5590

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Molnár-Institute for Applied Chromatography
Schneegloeckchenstrasse 47
10407, Berlin
Germany

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