Articles for Malvern Panalytical

Time-saving automation for exosomes analysis.

Jeff DeNigris, Malvern Panalytical, addresses the increasingly prominent role of the Industrial Internet of Things (IIoT) in the cement industry

Manufacturing industries using powder metallurgy (PM) techniques – including additive manufacturing (AM) and metal injection moulding – rely on a supply chain of closely specified, high-performance metal powders to produce precision components at a competitive cost.

This white paper explores a number of ways that today’s modern, laboratory-based PXRD instrumentation and advanced software can greatly assist pharmaceutical scientists in their quest to develop high quality, stable products and accelerate their speed to market.

This white paper outlines the main benefits of using hard radiation for material analysis studies. X-ray powder diffractometers are generally equipped with X-ray sources using Cu anodes. Often, people make use of synchrotron radiation, but new developments on source, optics and detector technologies allow a variety of hard radiation experiments in the home lab.

Rheometry refers to the experimental technique used to determine the rheological properties of materials; rheology being defined as the study of the flow and deformation of matter which describes the interrelation between force, deformation and time.

This paper describes the industrial applications, rather than the detailed description of methods such as Rietveld analysis, which is covered in great detail by Aranda et al. (2012, this volume). Different systems and software packages are available and in use.

This application note demonstrates that the Epsilon 4 is capable of analyzing sulfur and chlorine in waste oil.

“The brewing process includes several steps: malting, milling, mashing, lautering boiling, fermenting, conditioning, filtering and packaging."

Reducing the need for time-consuming and expensive TEM analysis with Zetasizer Ultra

Dynamic Light Scattering (DLS) is a powerful and sensitive technique for characterizing particles or macromolecules in dispersion, due to its ability to resolve particle or molecular sizes ranging from sub nanometer to several microns.

Gel permeation / size exclusion chromatography (GPC/SEC) is the most well-known method for polymer and macromolecular analysis. As the technique has become more pervasive, there has been a push toward greater efficiency, by way of reduced run times and minimal solvent and sample consumption.

“We are excited to bring this innovative, real-time image analysis technology to our customers in the United States. High-resolution visualization and quantitative analysis of particulate systems in situ and in near real time is an important enhancement to the characterization toolkit we deliver to research scientists and process engineers in many industries. SOPAT technology is complementing our range of solutions for on-line and in-process characterization and together with applications expertise of our technical team will deliver added value to our customers working on optimizing their products and processes.” said Alon Vaisman, Head of Sensors and Automation Solutions, Malvern Panalytical.

“Collaborating with a progressive innovator and highly respected leader such as Malvern Panalytical aligns with our strategic development to deliver greater value in analytical instrument solutions for our customers,” said Preston Hendrix, President of Micromeritics Instruments. “Micromeritics has always put our customers’ interests first, and this partnership is further proof of that commitment to deliver excellence in materials characterization.”

Malvern Panalytical, a global leader in high-performance analytical instrumentation and material analysis solutions, announced today that the company has received a US patent and Australian patent on its new solution for the multi-sensor analysis of complex geologic materials. The patent is centered around the ASD brand of near-infrared spectroscopy (NIRS) solutions, including the TerraSpec®and FieldSpec®instruments, that are part of the Malvern Panalytical family of products.

John Carpenter is a Professor of Pharmaceutical Sciences in the Department of Pharmaceutical Sciences at the University of Colorado, Anschutz Medical Campus. His laboratory is involved in researching the causes and control of aggregates and particles in t

Malvern Panalytical announced that it entered into a co-marketing agreement with Waters Corporation (NYSE:WAT) to advance the analysis of polymers. By pairing the Waters® ACQUITY® Advanced Polymer Chromatography® (APC™) System with Malvern Panalytical’s OMNISEC® REVEAL, R&D scientists can access higher sensitivity, higher resolution data than ever before, giving them better insight into their samples without the need for column calibration.

Malvern Panalytical wins Innovate UK grant to lead biopharmaceutical consortium on aggregation analytics

Malvern Instruments are exploring the relationship between molecular characteristics and bulk rheological properties of biodegradable polymers

Malvern discuss techniques for "Accelerating the Deformulation Workflow for Oral Solid Dosage Forms".

Malvern offer a new application note on "The Power of Multi-Detector SEC in the Analysis of Antibodies"

Malvern whitepaper investigates how rheology and laser diffraction can determine the mouthfeel of chocolatte from the pressure and snap of the first bite to the coating of the inside of the mouth.

Malvern present the second of three articles discussing principles, measurements and analysis in the application of dynamic light scattering to protein therapeutic formulations. In this section they discuss concentration effects and particle interactions.

Malvern present the third of three whitepapers discussing the use of Dynamic Light Scattering (DLS) in Protein Therapeutic Formulations. This article focusses on DLS deconvolution algorithms.

Malvern Instruments discuss how Nanoparticle Tracking Analysis can assist drug developers in assessing drug encapsulation.

Malvern Instruments presents a new whitepaper on the use of laser diffraction partice sizing to evaluate fuel/water separation efficiency in fuel filters and diesel engines.

The use of Nanoparticle Tracking Analysis as a rapid and information-rich multi- parameter nanoparticle characterization technique which allows the user to obtain number frequency particle size distributions of polydisperse nanoparticulate systems has resulted in its rapid adoption as an interesting new technique in a wide range of sectors within environmental and toxicity studies.

Many consumer products can have delicate microstructures which can be easily broken down during transportation and may not recover their original structure until a finite time has passed or in some cases not at all. This can have big implications for end product performance but also stability, since structural breakdown in a dispersion may lead to product separation.

Malvern discusses the process of tackiness measurement in adhesive materials using a rotational rheometer.

Malvern Marketing Manager, Renate Hessemann, gains an award marking nearly two decades of service on the Powtech advisory committee.

Malvern Instruments' Alan Rawle has been invited to speak at the Brian Scarlett Memorial Session, taking place at the World Congress for Particle Technology.

Malvern whitepaper explores the use of differential scanning calorimetry and isothermal titration calorimetry to study the thermodynamics of protein aggregation and misfolding.

Malvern whitepaper on the characterisation of fiber-like bacteria (Trichodesmium) using the Morphologi G3 with its wet cell accessory.

Malvern instruments present a new whitepaper on the characterization of biopharmaceutical stability with differential scanning calorimetry.

Whether you are isolating novel proteins for the first time, investigating the aggregation behavior of purified proteins in different conditions or evaluating the success of your conjugation; ultimately you have one thing in common: mixtures!

Foams are present in a large number of products, from personal care to food products and industrial products. The rheological properties play a critical role in foam characteristics, such as foam consistency and in the overall consumer acceptability and functionality of these products.

The ability to detect nanoparticle fluorescence is important when attempting to distinguish a particular subset of particles from within a complex background. Particles which are fluorescent can be measured in terms of particle size and concentration to understand the nature of those particles.

Malvern Instruments offer a free white Paper on ‘Developing A Bioformulation Stability Profile’ for the biopharmaceutical industry.

Malvern Instruments present a new application note detailing the use of differential scanning calorimetry to analyse blood serum and detect diagnostic cancer biomarkers.

NanoSight, Malvern Instruments' Nanoparticle Tracking Analysis method, is to be used by the Département Environnement et Agro-biotechnologies for toxicology studies.

Specialists from Malvern Instruments appear at Respiratory Drug Delivery 2014 to present new ways of accelerating development of DPI formulations with the Morphologi G3-ID particle characterization system.

Malvern Instruments’ applications manager, Dr Alan Rawle, talks TLAs in plenary lecture at Particulate Systems Analysis conference.

Malvern Instruments presents a new whitepaper explaining key terms and introducing important concepts for understanding Dynamic Light Scattering (DLS).

Malvern present the first of three whitepapers on the application of dynamic light Scattering (DLS) to protein therapeutic formulations.

Malvern Instruments application note exploring the use of the Morphologi G3 particle characterisation instrument to measure viscosity and other parameters in battery slurries.

When viscoelastic materials are deformed, they undergo a three dimensional deformation. Here, a rheological experiment shows the shear rates and stresses of a non-linear viscoelastic material and its behaviour.

Malvern Instruments discusses the characterisation of exosomes and microvesicles by means of Nanoparticle Tracking Analysis (NTA).

Malvern present a free white paper detailing how particle characteristics such as size, shape and zeta potential can affect the rheological properties and performance of particle suspensions.

A defining feature of polysaccharides, which are used widely as food additives and for certain medical applications, is that they are naturally occurring and consequently prone to inherent variability.

Discover the affects of particle size on the properties and behaviour off food and drink products and learn about a range of techniques for particle size analysis.

The widely used technique of GPC characterizes a wide variety of macromolecules. While conditions that are effective and practical have been determined, a change in conditions can lead to better improvements in cost and health and safety.

Malvern's application note describes the use of the Omnisec GPC / SEC system to study polymer branching in polyvinyl chloride and understand its effects on polymer characteristics including crystallinity, chain density and entanglements.

Malvern presents a new application note on Analysis of Polymer Degradation with Gel Permeation Chromatography (GPC) .

This application note from Malvern compares the analysis of acid- and ester-capped PLGA samples in DCM and THF mobile phases.

Malvern presents an application note on using GPC/SEC to determine the relative concentrations of components in polymer samples.

Malvern introduces the Hydro Sight™ laser diffraction dispersion accessory for the Mastersizer 3000 for rapid visualization and assessment of liquid particle dispersion during a measurement.

The Hydro SV small volume wet sample dispersion unit for the Mastersizer 3000 laser diffraction particle size analyzer allows effective particle size analysis with small quantities of sample and dispersant.

Malvern introduces new developments in interfacial measurement techniques. The company will be appearing at upcoming colloids conference events presenting developments in zeta potential measurement and high conductivity electrophoresis.

Malvern describe how to connect Viscotek detectors to Waters systems, in particular the Waters Alliance® system, and how to use their own OmniSEC software in combination with Empower® to run trouble-free separation sequences.

Malvern Instruments discuss the use of Morphologically-Directed Raman Spectroscopy (MDRS), which is a valuable tool for particle size, shape and chamical identification in the investigation of counterfeit pharmaceuticals.

Malvern introduce the MicroCal range of isothermal titration calorimeters for studying biomolecular interactions with applications ranging from drug design to fundamental research into signal transduction pathways.

Malvern present the Kinexus lab+ Rotational Rheometer with rSpace software for Standard Operating Procedure driven rheological testing in laboratory quality control.

Malvern presents a new article detailing how laser diffraction can help to measure particle size and distribution in metal powders used in the fabrication of small objects and components.

Malvern Instruments' Henrique Kajiyama explains how new laser-diffraction techniques enable measurement of particle size in highly concentrated emulsions, suspensions and slurries.

Malvern Instruments have announced an agreement with GE Healthcare Life Sciences to acquire the company's MicroCal business, with the acquisition expected to complete in the third quarter of 2014.

Malvern Instruments shows how complementary technologies solve analytical challenges from biopharm to bulk materials at Analytica 2014 from 1 - 4 April 2014 in Munich, Germany - find the in Hall A1, Stand 227

Malvern Instruments is the Premier Sponsor of PEGS China, where the company will present its analytical toolkit for biopharmaceutical development.

Malvern Instruments Specialist, Ciaran Murphy presents a session on ‘Nanomaterials Characterization Challenges' at Nanomaterials for Industry.

Unique metrology systems for molecular and nano-scale measurements complement Malvern Zetasizer Nano capabilities

In their next webinar, Malvern Instruments will be showing how new data has show the way in which RMM can ensure developers meet evolving regulatory challenges facing the biopharmaceutical industry.

Malvern Instruments has secured £3 million support from the UK Government's Regional Growth Fund, which will help create 47 new jobs.

Analytical solutions from Malvern Instruments nanoparticle tracking analysis instruments support University of Wisconsin-Milwaukee research into the environmental effects of nanomaterials.

Malvern's MicroCal PEAQ-DSC microcalorimeter resets the performance standard for characterizing protein and biomolecule stability.

The new Zetasizer NanoSampler from Malvern is a fully automated sample delivery system of nanoparticle and colloid characterisation for the Zetasizer Nano.

A recently published peer-reviewed paper is the 1000th to cite Malvern's NanoSight Nanoparticle Tracking Analysis system.

Malvern Panalytical collaborrates with IoT company, TetraScience, to develop smart laboratories and connected instruments embracing the Internet of Things.

Malvern scientists appear at the Biotherapeutics Analytical Summit to present new protein characterisation techniques and discuss techniques for understanding the association between protein colloidal and conformation stability.

Malvern puts the spotlight on cutting edge analytical strategies at ISFRS 2015

Malvern explores rheology for protein formulation and contributes a poster to the 2nd Protein-Protein Interaction Conference describing new work on rheological approaches to protein stability studies during biologics formulation.

Malvern releases a whitepaper on the application of Analytical Quality by Design for particle size assessment, an innovative approach to the validation of analytical methods.

Introducing the Zetasizer NanoSampler from Malvern, which provides automated sample delivery for the DLS system Zetasizer Nano, producing highly accurate results.

New accessories for the Mastersizer 3000, the Hydro Sight imaging accessory and Hydro SV small volume sample dispersion accessory support smarter pharmaceutical particle size analysis.

Malvern discuss the use of Nanoparticle Tracking Analysis to determine the environmental impact of nanomaterial wastes and contaminants.

Malvern's application note on "Measuring Exosome Stability with Nanoparticle Tracking Analysis" discusses how NTA can be used for measuring the size and concentration of exosomes stored at room temperature or 4ºC.

Malvern presents the measuring of protein molecular weight using their Viscotek SEC-MALS 20 multi-angle light scattering instrument which is connected to a Waters Empower® SEC system. A selection of proteins were used to demonstrate the measurement of protein molecular weight, oligomeric and aggregation state.

The MicroCal PEAQ-DSC Automated Differential Scanning Calorimetry instrument from Malvern is the gold standard for protein stability analysis in regulated environments.

Malvern's MicroCal PEAQ-DSC differential scanning calorimetry system represents the gold standard in microcalorimetry for applications in protein stability analysis for research.

Malvern present a new application note detailing the value of advanced, multi-detector GPC/SEC systems for comparison and characterisation of polysaccharide samples in the manufacture of goods from cotton and paper to pharmaceuticals and bioengineered products.

Malvern Instruments specialist appears at ISEV 2014 to present a paper on "Nanoparticle Tracking Analysis for Characterizing Extracellular Vesicles".

Malvern Instruments present a new whitepaper discussing how Nanoparticle Tracking Analysis can assist in the production of nanoparticles. The paper includes a summary of research involving nano-silica, nano-silver, gold and iron oxide nanoparticles.

Malvern Instruments appear at at BioNanoMed 2014 in Krems, Austria, to demonstrate NanoSight Nanoparticle Tracking Analysis for nanoscale particle characterisation.

Malvern have released a new brochure which provides a look into the range Viscotek Gel Permeation/Size Exclusion Chromatography detectors, available from the company.

Following the highly successful webinar series ‘Polymer Solution Characterization’, Malvern Instruments has released two new white papers that provide practical advice about characterizing polymers and measuring the rheology of polymer solutions.

Researchers are now using Malvern Instruments’ NanoSight Nanoparticle Tracking Analysis to examine extracellular vesicle yields from various cell culture lines.

Malvern introduce new OmniSEC software for control, data acquisition, analysis and reporting in the analysis of proteins and polymers with GPC/SEC chromatography.

PANalytical introduces the Epsilon 1 X-ray fluorescence (XRF) spectrometer, a powerful benchtop instrument for small spot analysis.

Malvern discuss the use of the Morphologi G3-ID for particle characterization of the active ingredients in pharmaceutical creams.

Malvern application note discusses the importance of particle size for the material properties of cement, and describes the use of laser diffraction for particle size analysis.

Particle size in sprays and aerosols is important in controlling both drug delivery and overall product performance in a wide and growing range of pharmaceutical applications.

Malvern application note on pharmaceutical excipient characterization. This application note will focus on two case studies on "Understanding excipient functionality in a formulation" and "Monitoring Excipient Blending".